Angiotensin II(血管紧张素Ⅱ)抗体试剂盒DHL/UPS快递到阿尔及利亚
产品背景
Angiotensin II is an essential component of the renin-angiotensinsystem (RAS), a potent regulator of blood pressure, body fluid andelectrolyte homeostasis. In response to lowered blood pressure, theenzyme renin cleaves angiotensinogen to produce angiotensin I(angiotensin 1-10). Angiotensin I is a substrate of ACE(angiotensin converting enzyme) that removes a dipeptide to yieldthe physiologically active peptide angiotensin II (angiotensin1-8). Angiotensin II acts directly on vascular smooth muscle as apotent vasoconstrictor, affects cardiac contractility and heartrate through its action on the sympathetic nervous system, andalters renal sodium and water absorption through its ability tostimulate the zona glomerulosa cells of the adrenal cortex tosynthesize and secrete aldosterone. Genetic variations inangiotensin II are a cause of susceptibility to essentialhypertension (EHT). Essential hypertension is a condition in whichblood pressure is consistently higher than normal with noidentifiable cause.
别名AlternateNames
Ang-II; Ang II; Angiotensin II; Angiotensin-2; AGT;Angiotensinogen; Serpin A8
应用说明ApplicationNotes
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
引用文献ProductCitations
[1] Zhang H et al. 2017. J Neuroimmunol. PMID 29169800. [2] Guo Wet al. 2016. PLoS One. 11(4): e0153434. PMID 27073902. [3] Wang C.et al. 2015. J Cardiovasc Pharmacol. 66(3):285-293. PMID 25955575.[4] Wang C et al. 2015. Acta Biochim Biophys Sin. PMID 26071572.[5] Matsuura-Hachiya Y et al. 2013. Biochem. Biophys. Res. Commun.442(1-2):34-43. PMID 24216112.
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AngiotensinII(血管紧张素Ⅱ)抗体试剂盒DHL/UPS快递到阿尔及利亚