treatment治疗
At present, there is no specific anti monkeypox drugs in China,mainly symptomatic support and treatment of complications.
目前国内尚无特异性抗猴痘病毒药物,主要是对症支持和并发症的治疗。
(一)
Symptomatic support treatment. Stay in bed, pay attention tosupplement nutrition and water, and maintain the balance of waterand electrolyte. For those with high body temperature, physicalcooling is the main factor, exceeding 38.5 ℃, and antipyreticanalgesics are given to reduce fever, but attention should be paidto prevent collapse caused by massive sweating.
对症支持治疗。卧床休息,注意补充营养及水分,维持水、电解质平衡。体温高者,物理降温为主,超过38.5℃,予解热镇痛药退热,但要注意防止大量出汗引发虚脱。
Keep the skin, mouth, eyes and nose clean and moist, and avoidscratching the skin of the rash to avoid secondary infection.Analgesic drugs can be given when the pain in the rash isserious.
保持皮肤、口腔、眼及鼻等部位清洁及湿润,避免搔抓皮疹部位皮肤,以免继发感染。皮疹部位疼痛严重时可予镇痛药物。
(二)Treatment ofcomplications. In case of secondary skin bacterial infection,effective antibiotics should be given, which should be adjustedaccording to the results of pathogen culture, isolation andidentification and drug sensitivity. Prophylactic use ofantibiotics is not recommended. When corneal lesions occur, eyedrops can be used, supplemented by vitamin A and other treatments.When encephalitis occurs, sedation, dehydration, intracranialpressure reduction, airway protection and other treatments aregiven.
并发症治疗。继发皮肤细菌感染时给予有效抗菌药物治疗,根据病原菌培养分离鉴定和药敏结果加以调整。不建议预防性应用抗菌药物。出现角膜病变时,可应用滴眼液,辅以维生素A等治疗。出现脑炎时给予镇静、脱水降颅压、保护气道等治疗。
(三)Psychological supporttreatment. Patients often have psychological problems such astension, anxiety and depression. They should strengthenpsychological support, counseling and related interpretation.According to the condition, they should timely ask a psychologicalspecialist for consultation and participate in the diagnosis andtreatment of the disease, and give corresponding drug adjuvanttreatment when necessary.
心理支持治疗。患者常存在紧张、焦虑、抑郁等心理问题,应加强心理支持、疏导和相关解释工作,根据病情及时请心理专科医师会诊并参与疾病诊治,必要时给予相应药物辅助治疗。
(四)Traditional Chinese medicine treatment. According to theprinciple of "judging the cause and treating the disease" and"adjusting the three factors", the treatment is based on syndromedifferentiation. Those with fever in clinical symptoms arerecommended to use Cimicifuga Gegen decoction, Shengsheng powder,Zixue powder, etc; It is recommended to use Qingying Decoction,Cimicifuga Biejia decoction, Xuanbai Chengqi Decoction, etc. forthose with clinical symptoms such as high fever, dense pox andrash, sore throat, and multiple lymph node swelling andpain.中医治疗。根据中医“审因论治”、“三因制宜”原则辨证施治。临床症见发热者推荐使用升麻葛根汤、升降散、紫雪散等;临床症见高热、痘疹密布、咽痛、多发淋巴结肿痛者推荐使用清营汤、升麻鳖甲汤、宣白承气汤等。
猴痘临床试验可以联系IVDEAR王小姐!